A lot of reviews will tell you that there isn't any actual gameplay in Serena and they're right. There are no items to pick up and use with other objects or locations within the cabin. You will find no puzzles to solve or characters to interact with. The style here is more of what I would call an interactive short story, a story that unfolds in a very dark and interesting way. Many locations and objects within the cabin have multiple pieces of dialogue to add to the narrative, which feels very candid and natural.
Pros
+Excellent and emotive voice acting in the narrations
+Atmospheric location and sounds
+Immersive graphical design
Cons
-As stated, there's no gameplay. If you're looking for a traditional point-and-click adventure then Serena isn't for you.
-With few exceptions, horror is implied, not overt. If you expect jump scares and monsters in your horror, look elsewhere.
Add Serena to your collection if you appreciate a good narrative and/or are a fan of "art" games.