Save yourself the headache.
I will openly say that I like the potential of this game, and Bowie is a huge plus. However, I cannot in good faith call this game good. I have a strange fascination with trying to beat it and have so far been unsuccessful. Also Bowie is only in the game for 10 minutes tops.
To start, this game looks bad. Even for the era it looked bad. Character models are poorly rigged and lack basic emotions, move like haunted puppets, and sport rather uncomfortable outfits. The game itself has four (yes, four) different control schemes for different aspects of gameplay, so you can jump from third-person exploration to first person shooting and have to remember what buttons do what. The ridiculous and clunky martial arts and swimming also have their own separate controls. You'll want to rebind those the moment you first start the game.
Ambition will only get you so far - this game just falls on its face. The concept is very interesting; you start as a cop trying to solve your own murder in a post-apocalyptic world, only to quickly get thrown head-first into misappropriated culture and oh no demons!! The game barely follows its own rules regarding the magick of the world, and requires in-depth walkthroughs to make any decent progress. One of the biggest flaws in this game is its point and click puzzles that usually only have one solution - that you have to find in a massively open world. This opens up several opportunities to softlock yourself without even trying. The game only bothers with a few "branching" options in the first district; after that they clearly just ran out of time. Lots of events foreshadowed in dialogue go out with a whimper and happen off screen.
The nomadic aspect of the soul-transfer had the potential to be an interesting mechanic, but it's not you body-hopping folks who lost their souls. You possess people to get what you want, and then ditch them. By the end of the game you are possessing people with the explicit intent of getting them killed so you can make something happen. You possess soldiers to sneak into and commit terrorist attacks on facilities, and prostitutes to seduce men into getting information out of them. If anything this could have made for a great twist where you find out you were the villain all along. But alas, it is just poorly thought out.
On a technical level, the game suffers from many bugs and crashes, and saves are a consumable item you have to find, so you better hope it doesn't crash while you're trying to ration them.
It really is a shame, because it had the potential to be so much more. As is however, don't bother.